CELL & GENE Therapy related products – TURBO NUCLEASE
Amamus Turbo Nuclease is a broad-spectrum endonuclease that cleaves both DNA and RNA molecules independently of being single- or double-stranded, circular, linear or supercoiled. The enzyme is highly stable and active in a broad range of pH and temperature, making it ideal for a variety of downstream processes that require the degradation of DNA/RNA in a simple, efficient and specific manner.
| Catalog # | Specifications | Size |
|---|---|---|
Application
- Reduction of viscosity from cell lysates
- Prevention of cell clumping
- Elimination of unspecific protein-DNA complexes prior 2D- or native gel electrophoresis
- Removal of nucleic acids from large-scale protein preparations
Features
- Endonuclease from Serratia macescens recombinant expressed and purified from E. coli
- Catalytic activity from pH 6 to 10 (optimal around 8.8) and temperature 0 to 44 °C
- High catalytic efficiency (34-fold greater than DNase I)
- Activity requires the presence of Mg2+ (optimum 2 mM)